Best Medicine Season 1 • TV Show
Best Medicine • TV Show • Rating 7.2 out of 10
seasons Season 1 Season 2
Seasons of Best Medicine
Best Medicine currently has 2 seasons and 14 episodes. Most episodes run for around 43 minutes, offering a comfortable mid-length viewing experience. The series is currently marked as "Returning Series". The most recently aired episode came out in 2026.
Best Medicine Season 2 • TV Show
release-radar
When does Best Medicine Season 2 come out?
According to the latest schedule, the next confirmed release for Best Medicine is Season 2, Episode 1, titled "Episode 1", which is set to air on September 22, 2026. That episode will open a brand new season, making it the official start of Season 2. Release times can differ slightly outside of United States of America, so your local broadcaster or streaming app may list a slightly different premiere date or time.
trailers
Watch the official trailers for Best Medicine
Watch the main official trailer for Best Medicine in one place. Most of these clips were released around December 2025, capturing the show at its peak marketing push. Use the carousel to sample the show's visual style, story hooks and production quality before you dive into full episodes.
Uploaded in December 2025
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overview
What is Best Medicine about?
Small town doctor. Big time issues. Martin Best is a brilliant surgeon who abruptly leaves his illustrious career in Boston to become the general practitioner in a quaint East Coast fishing village where he spent summers as a child. Unfortunately, Martin's blunt and borderline rude bedside manner rubs the quirky, needy locals the wrong way, and he quickly alienates the town, even though he's all they’ve got. It blends comedy and drama elements. The series reflects a distinct United States of America style and perspective. The story is shaped by its creator, Liz Tuccillo.
release-timeline
Release pattern and schedule for Best Medicine
Best Medicine has been releasing episodes between January 2026 and April 2026 across 2 seasons. So far there are 14 released episodes, giving you plenty of story to catch up on before the next drop. The gap between seasons has often been under a year (around 3 months on average), indicating a relatively fast turnaround between batches of episodes. The upcoming release currently points to September 2026 as the key month to watch for new content.
catchup
How to catch up before the next Best Medicine release?
Best Medicine currently spans 2 seasons and 14 episodes, making it a manageable rewatch before the next release. Most instalments run for around 43 minutes, so a full-season binge can fit into a few dedicated evenings or a single weekend. If you're returning to the show, the latest storyline leaves off at Season 1, Episode 13, so rewatching the final season or two can help refresh the details before the next release.
cast
Cast and creators of Best Medicine
The main cast includes Josh Charles, Abigail Spencer and Josh Segarra. Behind the scenes, it is created by Liz Tuccillo.
Josh Charles
as Dr. Martin Best
Abigail Spencer
as Louisa Glasson
Josh Segarra
as Sheriff Mark Mylow
Cree Cicchino
as Elaine Denham
Annie Potts
as Aunt Joan